[Juvenile Sapho a two cases reports]

The acronym Sapho syndrome [for synovitis, acne, pustulosis, hyperostosis, osteitis] is a rare entity, particulary in pediatric patients. A 15 year-old and 19 year-old adolescents, with severe acne history, presented inflammatory buttock pain associated to lumbar pain in the first case and sternal pain in the second. Radiographic exploration demonstrated bilateral sacro-iliitis associated to sterno-clavicle arthritis in the second case. Diagnosis of Sapho syndrome was retained. Satisfactory improvement was caused by corticosteroids in the first case and non steroidal anti-inflammatory drugs in the second. Sapho syndrome is rare disease with unknown origin. Non steroidal anti-inflammatory drugs are the treatment of choice, as they are usually both effective and well tolerated

[Primary synovialosarcoma: a case of unusual location]

Report a new case of primary Synovi alosarcoma. We report a case of a 16 year old girl, who presented with a tumefaction on the right clavicle evolving or 3 months. Various explorations carried out, in particular thoracic scanner and imagery by magnetic resonance, showed a multilocular cystic formation of the seat and the clavicle reaching the mediastinum. A pathological examination of the part [piece] highlighted a biphasic synovialosarcoma of grade III. This diagnosis was validated by the immunohistochemistry study and the detection of transcribed specific fusion of the synovialosarcoma, SYT-SSXI. The unusual locations of the primitive SS must be known because the diversity of their microscopic aspects may cause confusion in the diagnosis. The immunohistochemistry, and more recently the cytogenetic studies, helps to solve these problems of differential diagnosis

[Nevus lipomatosus cutaneous giant of hoffmannn zurhelle a case report]

Nevus lipomatosus cutaneous superficialis [NLCS] of Hoffmann-Zurhelle is a rare hamartomatous skin lesion histologically characterised by the presence of mature fat tissue within the dermis. Clinically, two types of NLCS are distinguished: a multiple type and a solitary type. Illustration of anatomoclinical presentation of this rare lesion and the hypothesis of its pathogenesis. We report a case of a NLCS diagnosed in a 16-year-old girl, which was exceptional by its huge volume. This lesion was localised in the right thigh. The patient underwent wide excision of the mass without complication. The tumoral form is rarely reported in the literature, and its pathogenesis is unknown

Sciatica as a rare symptom of recurrent uterine carcinoma. About four cases and literature review

The occurrence of inflammatory sciatica needs a special attention because it is often related to malignant, infectious or inflammatory affections. However, rare pelvic affections and especially gynecological conditions can also cause sciatic pain. We report four observations of sciatic neuropathy caused by compression of the sacral plexus by metastases of uterine carcinoma. A literature revue is also undertaken to emphasize on the importance of recent complementary exams for the etiological diagnosis of sciatica

[Clear cell sarcoma [malignant melanoma] of soft parts: report of a case]

Clear cell sarcoma [or malignant melanoma] of soft parts is a rare malignancy that is found in the young adults and is generally located in the extremities of the limbs. In this study, we report a new case diagnosed in a 23-year old male revealed by a slowly enlarging mass of the knee. The histopathologic pattern of the mass was composed of nests and stands of fusiform or round cells alternating with bands of sclerotic stroma. The tumoral cells presented abundant, eosinophilic and sometimes clear cytoplasm. Some cells contain brown pigment which is Fontana [+]. Vimentin, S100 protein and HMbeta45 antibodies were expressed by the tumoral cells confirming the diagnosis of soft tissue clear cell sarcoma. Large surgical resection was performed with no recurrence eight months after